Taishida LYOBETA R&D Pilot Freeze Drying Machine

The LyoBeta series products are designed with a compact structure, with all components integrated into the box and equipped with casters for easy movement. The vacuum, refrigeration system, and other necessary components are fully configured and connected to public facilities for use.

Advanced design concepts

This series of products provides a systematic solution for the R&D center's exploration of freeze-drying technology.LyoBeta is equipped with various appropriate components, devices, and sensors to control temperature, pressure, and time, providing sufficient control for various processes and ensuring their repeatability.

This equipment includes a plate heat exchanger and other high-quality components to ensure that our freeze-drying machine can achieve a heating and cooling rate of 1 ℃/minute (the same as industrial freeze-drying machines).

The isolation valve between the sample chamber and the condenser has a dual function. On the one hand, it can be used for pressure rise experiments to determine the endpoint of freeze-drying; On the other hand, samples can be loaded and unloaded directly without defrosting when the condenser is not fully loaded.

The refrigeration system can achieve a condenser temperature of -80 ℃ and a laminate temperature of -60 ℃. Only using HFC environmentally friendly refrigerants ensures that the environment is not polluted and can be used for a long time.

Flexible applications

By using a capping device, the spacing between the layers can be easily adjusted,Suitable for bottles of various capacities, sizes, and types.In addition, there is an interface left on the side of the freeze-drying machine for connecting 6-port multi manifold, which can freeze open freeze-drying bottles of CN29/32.

Outstanding quality, outstanding craftsmanship

The sample chamber and layer board use the same structure and materials as the industrial freeze dryer.The manufacturing material is 316L stainless steel and all internal components are designed to be easy to clean. The condenser is also made of 316L stainless steel and equipped with an electric heating rapid defrosting device. The sample chamber and condenser are both equipped with transparent acrylic doors for easy observation of the entire freeze-drying process.

Control and temperature uniformity

Sandwich style laminated board with thermal conductive silicone oil circulation channels inside. This structure enables the product to achieve temperature control during in-situ pre freezing and sublimation stage heating.The top layer of heat radiation board is used to ensure that all samples on the board are uniformly heated.

Usually, the vacuum sensor of the freeze-drying machine used in research and development is installed on the vacuum channel to reflect the vacuum degree inside the chamber. The LyoBeta device has a vacuum sensor located inside the chamber, which directly reflects the actual vacuum level of the environment in which the sample is located.This enables the pilot research department to obtain reliable amplification results.

Taishida LYOBETA R&D Pilot Freeze Drying MachineThe main feature is the use ofPLCReplaced the microprocessor used in traditional models of this type. All industrial freeze dryers usePLCSystem. So using the same system in the pilot freeze-drying machine can achieve a wider range of resultsEnsure the reliability and repeatability of the process,Simultaneously make the device comply withcGLPstandard.

Through the human-machine interface（HMI）Implementing control over the freeze-drying process mainly includes:

*Information display of main components of the system (valves, motors, indicators, etc.)

*Alarm information reception

*Display of parameters in freeze-drying cycle process

*Eliminate the possibility of misoperation

*Protecting the system through authorization of the operator

*Development of freeze-drying process

*adoptUSBInterface download information

The user interface is a very prominent and easy to understand interface6.5Inch color touch screen display. Through this touch screen, various parameters of the freeze-drying process can be quickly inputted.

Alternatively, as an option, the device can also be connected to different peripherals such as chart recorders, printers, etcPCConnectedPCYou can use both the original operating interface and directly access itWindowsControl the interface.

Lyologger

Data collection software that collects charts, events, alarms, and historical records through serial ports（ASCIICode files, etc

LyoStar/Lab

Specially designed for research and developmentSCADAProgram software. It can design, load and store process programs to record the freeze-drying process in real time, draw freeze-drying curves, generate reports, historical records, alarms, etc.

accord with21 CFR 11Standard.