Embolic microspheres: mainly used as embolic agents in vascular embolization interventions, they are injected into the blood supply vessels of the target organ to achieve the therapeutic effect of interrupting the blood supply to the affected organ. Traditional embolization supplies include gelatin sponge and iodized oil+Chemotherapy drug suspension, biological gel, spring coil, and drug loaded elution embolization microspheres have overcome the shortcomings of traditional embolization products in drug delivery and embolization effect, becoming the ideal embolization preparation at present. In recent years, there has been a lot of research on drug loaded microspheres, but successful products are very rare. The technical challenges that need to be solved behind them mainly include the biocompatibility, ease of manipulation, and suitability of microspheresScalability and ResilienceIn order to achieve a complete embolization effect.And the impactThe physical properties of microspheres and embolic drug delivery, such as elasticity and recovery, can be determined by the Shanghai Baosheng Physical Property TesterConduct objective and accurate measurements.

The main ones currently listed are in the UKBiocompatibles' DC beadEmbolic microspheresandHepasphere from BioSphereEmbolic microspheresCurrently, only Jialisheng, a subsidiary of Hengrui, has obtained registration approval for drug loaded microspheres in China. The product isCalliSpheres drug loaded embolization microspheres and 8Spheres conformal embolization microspheres, bothFor polyvinyl alcohol embolization microspheres. Hepatic artery chemoembolization is widely used worldwide for the treatment of unresectable tumors and is considered a treatment method for advanced liver cancer. From the perspective of technological path, drug loaded embolization microspheres have good application prospects. Hengrui Jialisheng has been at the forefront of technology, and its product advantages are significant, which is expected to compete with foreign products in the future. Hengrui Pharmaceutical Procurement Shanghai BaoshengThe TA.HTC-20 physical property analyzer uses a highly stable servo motor for precise micro force measurement of Hengrui Pharmaceutical in its pharmaceutical materials field.

In the process of intervening in the development of the medical device industry, minimally invasive intervention therapy for treating vascular diseases is one of the representative technologies, and related implantable devices and consumables products are also developing rapidly; At the same time, the high incidence rate and high mortality of cardiovascular diseases promote the development of cardiovascular intervention.

Among them, drug-eluting stents are particularly widely used in cardiovascular intervention surgery, but currently this treatment method has some hidden dangers, such as the risk of "stent embolism" and bleeding after surgery. There is no high-quality treatment plan for in stent restenosis lesions, and the rate of in stent restenosis recurrence after simple balloon dilation surgery is also high.

Regarding these issues,drug-coated balloon(DCB)providedadvancedThe solution, doctors canDirectly delivering the balloon to the site, dilating the blood vessels, leaving medication at the affected area before exiting, thus achieving the effect of no foreign body implantation, greatly reducing the probability of intimal hyperplasia caused by stent implantation, and also preserving more clinical options for vascular treatment in the future.The rigidity of microspheres during transportation directly affects their medical efficacy.

Drug balloon used to open blockages

Shanghai Baosheng Physical Property Tester

Shanghai BaoshengTA. XTC-20Physical property analyzerAdopting high-precision motors with high-frequency signal acquisition capability, this microBall, embolismThe hardness and rigidity of materials, the elasticity of microspheres and microcapsules, the cohesion of hydrogel particles and other indicators can accurately obtain data. At the same time, the instrument has its own method library, which constantly builds application programs according to standard requirements. It is an instrument in the field of micro force. For more application details, please follow Shanghai Baosheng.

The consumables in the medical and health field are undergoing refined development, such asEmbolization, microspheresMicroneedles, microcapsules, hydrogel particles, etc,Mechanical performance is a key factor affecting its effectiveness in useTherefore, in the early stage of fine consumables research and development, it is necessary to adoptLike Shanghai BaoshengTA. XTC-20Physical property analyzerHigh precision mechanical analysis instrumentsMicrospheres, embolizationDuring useMicrosphere embolization rigidity, microsphere embolization elastic modulus, microsphere embolization recovery, etcAnalyze the mechanical properties.

At present,drug-coated balloonIt has become a treatment option for restenosis within the stent. Experts have pointed out that drug coated balloons will achieve rapid penetration and replacement of drug-eluting stent treatment methods in the fields of coronary artery and peripheral intervention. If penetration and replacement are sufficient, the domestic market space is about 115Billion yuan, and it is expected to maintain it annually in the future20%Rapid growth on both sides.By using the Shanghai Baosheng Physical Property Tester, it is possible todrug-coated balloon、Accurate measurement of microsphere, embolization rigidity, and recovery.

With the increasing incidence rate of atrial fibrillation in China——Currently, there are patients with atrial fibrillation who have exceeded1000Wan, in addition, currently there are only imported products listed in the Chinese marketBoston ScientificofWatchmanandSt.Jude MedicalofACPThe vast market space and relatively blank supply also provide better growth soil for local enterprises. Dai Zhihao revealed that the company's left atrial appendage occluder system has completed half of its clinical trials with good data feedback. If it is launched in the future, there is an opportunity to carry out import substitution.