UniSil ®-- Low back pressure, high column efficiency packing

Nano micro technology chromatography fillers have perfect spherical shape and high particle size uniformity. Compared with fillers with wide particle size distribution on the market, they have the advantages of easy column loading, low back pressure, high column efficiency, stable column bed, high resolution, uniform flow rate, and good column permeability. At the same time, nano micro fillers without fragments or small particles can also avoid problems such as screen clogging.

Figure 4. Relationship between particle size distribution and flow velocity characteristics.

UniSil ® -- Innovative surface bonding and tail sealing technology

Nano Micro Technology not only possesses the world's most advanced silicone synthesis technology, but also has developed innovative surface bonding tail sealing technology, making UniSil Nano Micro Technology ® The series of silicone chromatography fillers have better acid and alkali resistance and better selectivity. Nano Micro's patented technology covers everything from the synthesis of silicone matrix to surface bonding. Advanced instruments, equipment, and application technologies ensure the stability of silicone quality and the repeatability between batches of products. Nano Micro Technology provides customers with various specifications of polar or non-polar bonded phase (C18, C8, C4, Ph, NH2, CN, Diol, Triazole) silicone fillers to meet the needs of different customers.

In order to investigate the surface bonding and sealing of silicone, we studied UniSil? 5-120 C18 fillers were studied. Experiments have shown that the chromatographic peaks of various substances, including pyridine (alkaline compound), are sharp, symmetrical, and have high column efficiency, indicating the UniSil of nanotechnology ® The residual silicon hydroxyl groups on the surface of 5-120 C18 filler are minimal, and the tail sealing is good.

UniSil ®– Excellent chemical stability and acid alkali resistance

The unique bonding and sealing technology of Nano Micro Technology enables its silicone fillers to have better acid and alkali resistance. In order to verify the acid and alkali resistance of the silicone fillers of NanoMicro Technology, we used UniSil ® Enhanced acid and alkali resistance comparison tests were conducted between 10 μ m C18 silica gel packing and internationally renowned brand silica gel packing. The silica gel columns installed separately were washed repeatedly with 0.1 mol/L sodium hydroxide/methanol and 0.2 mol/L acetic acid/methanol, and the column efficiency was tested separately. The results showed that under strong acid-base washing, the column efficiency of internationally renowned brands rapidly decreased and lost its effectiveness, while the silica gel column efficiency of Nano Micro Technology was well maintained, indicating that Nano Micro Technology's unique tail sealing technology makes the silica gel packing have stronger acid and alkali resistance and longer service life.

Large scale production capacity and good inter batch reproducibility

Advanced large-scale silicone production equipment ensures that the production capacity of nano and micro materials can meet the needs of industrial chromatographic separation, and a reliable quality control system ensures the high quality and good inter batch reproducibility of our chromatographic fillers (as shown in the figure). Before leaving the factory, each batch of products must undergo strict quality testing (including parameters such as particle size, particle size distribution, pore size, and specific surface area) to ensure stable product quality. At the same time, a series of application tests are conducted to ensure stable product performance.

UniSill ® Pre installed chromatographic column

The goal of Nano Micro Technology is to provide customers with the highest quality, most stable performance, and most complete range of chromatographic packing materials and chromatographic pre columns. We can provide standard pre installed columns for analysis and preparation, or customize them according to customer needs. All pre installed columns of Nano Micro Technology undergo rigorous testing to ensure the high quality and stability of the chromatography columns.

Please click to download the packing experiment case by yourself: Packing experiment case