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LA8080 Ultra High Speed Fully Automatic Amino Acid Analyzer
LA8080 inherits and develops Hitachi's years of experience in the research and development of amino acid analyzers, with high reliability, stability,
Product details
LA8080 Ultra High Speed Fully Automatic Amino Acid Analyzer
LA8080 inherits and develops Hitachi's years of experience in the research and development of amino acid analyzers, with high reliability, stability, and excellent performance.
Fully automated operation, even beginners can easily use it. Fully consider the user's operational perspective and create a comfortable operating environment.
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characteristic
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application
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index
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Developer's Voice
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Research and Development History
characteristic
Ergonomic design
Consider various factors such as the user's field of view and operating habits.
easy to operate
The instrument design is exquisite and adheres to the concept of pre design. The instrument is of moderate height, making it convenient to hold reagent bottles and samples.
Space saving design
Adhering to the high reliability and stability of Hitachi amino acid analyzers, there are also options for floor standing and desktop models. The desktop design is compact, reducing the instrument volume by 30% and allowing it to be placed directly on the experimental bench, saving space.
Adopting a highly reliable and stable post column derivatization method with indene ketone
Adhering to the excellent analysis methods of previous models.
High reliability and stability analysis techniques
Adhering to the analysis method of the previous model, seamless connection, please feel free to use.
Analysis Example: Standard Analysis Method (Protein Hydrolysis Method)
Please select the analysis method for testing according to the experimental purpose. Commercial buffer solutions and derivative reagents can be used directly without the need for preparation. Indene ketone derivative reagents are unstable and generally require refrigeration storage, but Hitachi amino acid analyzers mix the two solutions in real time before the derivative reaction and do not require refrigeration.
A wide range of applications
Up to 6 buffer solutions can be used, and the column temperature box can also be set with time gradient temperature control, allowing users to flexibly create analysis methods.
application
| AS/AAA-001_C | Biological Sample Analysis - Amino Acid Composition Analysis | download |
| AS/AAA-002_C | Analysis of Biological Samples - Amino Acid Detection in Culture Media | download |
| AS/AAA-003_C | Determination of samples included in the 16th edition of the Japanese Pharmacopoeia | download |
| AS/AAA-004_C | Analysis of Chain Chains and Isochain Chains in Elastic Protein Food Raw Materials | download |
| AS/AAA-005_C | Biopharmaceutical Analysis - Composition Analysis of Oxytocin Amino Acids in Peptide Preparations | download |
| AS/AAA-006_C | Biopharmaceutical Analysis - Amino Acid Composition Analysis of Peptide Preparations with Calcitonin | download |
| AS/AAA-007_C | Determination of dipeptides (alanylglutamine) amino acids in culture medium | download |
| AS/AAA-008_C | Biopharmaceutical Analysis - Amino Acid Composition Analysis of Peptide Preparations with Calcitonin | download |
| AS/AAA-009_C | Determination of L-alanine | download |
| AS/AAA-010_C | Determination of L-lysine acetate | download |
| AS/AAA-011_C | Determination of L-Proline | download |
| AS/AAA-015_E | Analysis of the Storage Stability of Glutamine and Tryptophan | download |
| AS/AAA-016_E | Analysis of protein and amino acids in chicken meat | download |
| LC080049_E | Analysis of Standard Amino Acids in Soybean Powder by Protein Hydrolysis Analysis Method | download |
| LC080050_E | Free amino acids in sugarcane, cucumber, watermelon, and supplementary beverages | download |
| LC090033A_E | Analysis of Amino Acids in Combination Feed | download |
| LC090034A_E | Analysis of Amino Acids in Rabbit Feed | download |
The course focuses on the basics of high-performance liquid chromatography, including "Principles and System Configuration of High Performance Liquid Chromatography" and "Advantages of Various Detection Methods".
- Basic Course on High Performance Liquid Chromatography
- Repair and Service
index
Indicator (Protein Hydrolysis Method)
| Net analysis time | 30 min (Net) |
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| Retention time reproducibility | CV 0.3 % (Arg) |
| Peak area reproducibility | CV 1.0 % (Gly, His) |
| detection limit | 2.5 pmol (S/N=2, Asp) |
analysis unit
| chromatographic column | Size: 4.6 mm ID x 60 mm* |
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| Resin: Hitachi specific ion exchange resin | |
| Infusion pump | Flow range: 0.001-1.000 mL/min |
| Conveying pressure: 0-34 MPa | |
| 6 types of buffer gradient separation | |
| autosampler | Injection method: direct injection |
| Sample bottle volume: 1500 µ L | |
| Sample bottle quantity: 120 (refrigeration unit (optional): 100) | |
| Injection volume: 0.5-100 µ L (standard injection) | |
| Column temperature box | Method: Peltier temperature control |
| Set temperature: 10-90 ° C (increments: 1 ° C) | |
| Reaction unit | Method: Reactor |
| Set temperature: 50-140 ° C (increments: 1 ° C) | |
| detector | Spectral system: phase corrected concave diffraction grating |
| Wavelength: 570 nm, 440 nm |
other
| Exterior dimensions (excluding computer) | 700(W)×600(D)×1,380(H) mm |
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| Weight (excluding computer) | About 175 kg |
| temperature range | 15～35 °C |
| Power Supply | 220, 230, 240 V ± 10 V, 800 VA, 50 or 60 Hz |
| nitrogen | User provided |
- *Standard chromatographic column
Developer's Voice
Excellent performance, compact design, easy operation
The new generation of amino acid analyzer is born!
Hitachi High Speed Amino Acid Analyzer LA8080
In 1962, Hitachi launched the first amino acid analyzer, which greatly promoted the detection of amino acid components in feed, food, and medicine. LA8080 is based on the classic model L-8900 launched in 2005 and has been carefully crafted for over a decade before being launched to the market.
LA8080 adheres to three major concepts:
Firstly, it has excellent performance. Multiple exclusive Hitachi technologies have further improved performance.
Secondly, the design is compact. Retain the classic landing version while adding a desktop version. Minimize the footprint of the instrument to save laboratory space and place it directly on the experimental bench.
Thirdly, it is easy to operate. From the perspective of ergonomics, improve experimental efficiency.
Hitachi High Speed Amino Acid Analyzer LA8080 adheres to exclusive technology, leads innovation, and is committed to providing high-performance instruments and diverse solutions for amino acid analysis customers.
Research and Development History
History of Hitachi Amino Acid Analyzer
The development process of Hitachi amino acid analyzer
Amino acid analyzer is an instrument used for quantitative analysis of each amino acid component in solution samples. It is mainly used for quality management of food, drugs, and feed, as well as in fields such as biochemical research and third-party testing.
In 1958, Spackman, Stein, and Moore pioneered the amino acid system separation technology and automatic analysis method using post column derivatization with indene ketone.
In 1962, Hitachi's Naco factory successfully developed Japan's first amino acid analyzer KLA-2, marking the beginning of the glorious history of Hitachi's amino acid analyzer. At that time, analyzing a sample required a whole day's time (22 hours). In 1977, Hitachi introduced the new model 835, which had an ion exchange resin diameter of only 5 μ m in the chromatography column, significantly reducing the particle size compared to the first generation model. The analysis speed has also made a qualitative leap, and the analysis time has been shortened to 50 minutes. In addition, with the optimization of the detection system, the sensitivity has reached over 1000 times that of KLA-2.
In late April 1977, a Japanese fishing boat salvaged a body resembling a reptile in the waters off New Zealand. The body had huge fins and was suspected to be a long necked dinosaur. The 'sea monster' incident caused a sensation worldwide for a time. In order to investigate, Hitachi brought the front fins on the deck to the Naco factory and conducted amino acid composition testing using the latest 835 model at that time. The results showed that the sample was composed of characteristic proteins such as hydroxyproline and oxylysine, indicating that it was a scaly fin strip on the shark fin. On July 25th, this news dominated the pages of the national morning newspapers, and the sea monster theory was exposed in just three months.
Afterwards, Hitachi launched the L-8500 in 1986, using the industry's first 3 μ m ion exchange resin, which shortened the analysis time to 30 minutes. The L-8800 was launched in 1977, marking the first computer-controlled derivative using a reaction column. In 2005, the L-8900 was launched with superior performance, built-in methods, and easier instrument operation, becoming a classic model and deeply loved and trusted by Chinese customers.
The latest model LA8080 was launched in 2017. It inherits the excellent performance and data reliability and stability advantages of Hitachi amino acid analyzer, while also introducing a compact desktop design to solve the practical problem of insufficient laboratory space.
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- Allusions from: Masato Ito, Yuko Narimatsu, Toshihide Pei, Atsushi Morizaki, Yuzhi Suzuki, Shinto Fukuda, Takashi Yagi, Shigeru Otsuki, Kazuya Sekigahara, Kenji Toyosaki S. I. NEWS, 61, 5360-5364 (2018).
- https://www.hitachi-hightech.com/cn/about/news/2020/.html?version=
Development History Video of Hitachi Amino Acid Analyzer
Introduction to the application of amino acid analyzer in the pharmaceutical field
Contains 12 detection examples and appendix information.
Listed application examples in the fields of medicine and biopharmaceuticals included in the 16th revision of the Japanese Pharmacopoeia.
For other details, please consult us.
application
Introduce a measurement example of a fully automatic amino acid analyzer.
Basic Course on High Performance Liquid Chromatography
Introduce the basic knowledge of high-performance liquid chromatography, including the principles and system composition of high-performance liquid chromatography, as well as the characteristics of various detection methods.
Science Environment
Introduce the symbol of Hitachi High Tech Science Group, which aims to become a leader in the technology field.
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