High precision chromatographic signal acquisition: 24 bit high-precision chromatographic signal acquisition in various forms;

Add user management, permission settings, electronic signatures, and audit tracking functions;

Compliant with GLP/GMP ISO9001、21 CFR Part11、 2015 Pharmacopoeia and CTD format requirements;

Powerful post-processing capabilities: powerful functions such as spectral comparison, recalibration, and data input and output;

Wide applicability and support for multiple detectors: can be connected to any gas chromatograph, liquid chromatograph, or electronic device with voltage output, and can simultaneously collect signals from one to two independent detectors;

Software interface friendly and easy to operate: software developed based on Windows 32-bit system, user-friendly graphical user interface, familiar window operation style makes chromatography easier to operate;

Batch processing function: automatic sampler sequence acquisition, automatic integration correction, and output report can all be completed synchronously, simplifying daily tedious analysis;

The system adaptability evaluation (SST), manual integration, internal and external standard calculation, report style and other functions have been enhanced, making the operation simpler and more convenient, and the calculation more accurate;

The Chinese operation interface conforms to the function key setting and operation process used by Chinese people, and is more suitable for countrymen people than the chromatography workstation with the same performance abroad.

Liquid phase detection application

High performance liquid chromatography HPLC detection scheme for doxycycline hydrochloride

-Sample processing procedure-

Accurately weigh an appropriate amount of doxycycline hydrochloride reference substance, add an appropriate amount of 0.01mol/L hydrochloric acid solution, dissolve by ultrasound, and dilute with 0.01mol/L hydrochloric acid solution to a solution containing approximately 1mg doxycycline hydrochloride per 1ml. Shake well, filter through a 0.45 µ m organic system filter membrane, accurately measure 20 µ L, inject into a liquid chromatograph, and record the chromatogram.

-Chromatographic conditions-

Chromatographic column: C18, 4.6 mm*250 mm， Particle size 5 µ m

Mobile phase: Acetonitrile: Acetate buffer solution=25:75

Wavelength: 280nm

Flow rate: 1.0mL/min

Instrument configuration:Please click to view the image details

Overall performance

Number of input channels: 2 (two channels can be merged and displayed on the same interface);

Input voltage range:- 2.5V ～+2.5V；

Input impedance:> 10MΩ；

Integral sensitivity: 1uV • second;

Minimum signal resolution: 1uV;

Dynamic range: 107;

Minimum time resolution: 0.01min;

Linearity: ± 0.1%.

Peak processing capability

Number of peaks that can be processed: greater than 1000 (related to computer resources);

Minimum peak width that can be processed: 0.1 seconds;

Equipped with an automatic time program;

Equipped with manual integration function;

Can automatically recognize various complex peak shapes and accurately segment them;

Baseline automatic tracking and calibration;

Automatic elimination of negative peak effects;

Compliant with GMP regulations;

Qualitative identification method for spectral peaks:

Retention time method;

Component table identification method.

Integral parameter

Peak area or peak height;

Quantitative calculation method:

Normalization method;

Internal standard method;

Grouping method;

Multi internal standard method;

External standard method.